Environment Can Influence Genetic Expression

See also Dr. Noble’s information on this newer understanding that adds layers of difficulty to the classic story of evolution (see also my post on quantum biology that is adding to the complexity of this issue). The following is from PHYS-ORG:

…New research from the University of Maryland provides a surprising possible explanation. For the first time, developmental biologists have observed molecules of double-stranded RNA (dsRNA)—a close cousin of DNA that can silence genes within cells—being passed directly from parent to offspring in the Caenorhabditis elegans. Importantly, the gene silencing effect created by dsRNA molecules in parents also persisted in their offspring.

[….]

“This is the first time we’ve seen a dsRNA molecule passing from one generation to the next,” said Antony Jose, an assistant professor in the UMD Department of Cell Biology and Molecular Genetics and senior author on the study. “The assumption has been that dsRNA changes the parent’s genetic material and this altered genetic material is transmitted to the next generation. But our observations suggest that RNA is cutting out the middle man.”

Jose and his team, including graduate student and lead author Julia Marré and former research technician Edward Traver, introduced dsRNA marked with a fluorescent label into the circulatory system of C. elegans worms. They then watched as these fluorescent RNA molecules physically moved from the parent’s circulatory system into an egg cell waiting to be fertilized.

In a surprising turn of events, some of the dsRNA molecules could not silence genes in the parent because the dsRNA sequence did not match any of the parent’s genes. But the dsRNA molecules did silence genes in the offspring, when the new worm gained a copy of the matching gene from its other parent. This suggests that, in some cases, gene silencing by dsRNA might be able to skip an entire generation.

“It’s shocking that we can see dsRNA cross generational boundaries. Our results provide a concrete mechanism for how the environment in one generation could affect the next generation,” Jose said. “But it’s doubly surprising to see that a parent can transmit the information to silence a gene it doesn’t have.”….

What is a Gene? (Denis Noble vs. neo-Darwinism)

The larger, original file, can be found here and is well worth the watch if this subject intrigues you. I wanted to isolate how Denis Noble defines “what a gene is”? To wit, a great question starts out the above video — and as science advances, the neo-Darwinian model weakens immensely. See Dr. Noble’s lecture on this:

I do wish to add that biology… our physiology really, is also made via influences on the quantum level. ALL THIS is to say that the simplistic view of “gene to organism” is a lagging theory NOT based in current science… AND, it makes the irreducible complexity issue worse for the naturalist. For further reading on the newer field of “quantum biology,” see my post HERE. May I also note that my professor of apologetics WAAAY back in 2007 was noting this in his class. I bemoaned him then, but “bow down” to his foresight now.